Direct regulation of E-cadherin by targeted histone methylation of TALE-SET fusion protein in cancer cells

TALE-nuclease chimeras (TALENs) can bind to and cleave specific genomic loci and, are used to engineer gene knockouts and additions. Recently, instead of using the FokI domain, epigenetically active domains, such as TET1 and LSD1, have been combined with TAL effector domains to regulate targeted gen...

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Detalles Bibliográficos
Autores principales: Cho, Hyun-Soo, Kang, Jeong Gu, Lee, Jae-Hye, Lee, Jeong-Ju, Jeon, Seong Kook, Ko, Jeong-Heon, Kim, Dae-Soo, Park, Kun-Hyang, Kim, Yong-Sam, Kim, Nam-Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695155/
https://www.ncbi.nlm.nih.gov/pubmed/26125227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695155/
https://www.ncbi.nlm.nih.gov/pubmed/26125227

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