Lovastatin overcomes gefitinib resistance through TNF-α signaling in human cholangiocarcinomas with different LKB1 statuses in vitro and in vivo

Gefitinib resistance has been shown to complicate cancer therapy. Lovastatin is a proteasome inhibitor that enhances gefitinib-induced antiproliferation in non-small cell lung cancer. The objective of this study is to investigate the mechanism of lovastatin-induced antiproliferation in gefitinib-res...

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Detalles Bibliográficos
Autores principales: Yang, Sheng-Huei, Lin, Hung-Yun, Chang, Vincent H.S., Chen, Chien-Chung, Liu, Yun-Ru, Wang, Jinghan, Zhang, Keqiang, Jiang, Xiaoqing, Yen, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695157/
https://www.ncbi.nlm.nih.gov/pubmed/26160843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695157/
https://www.ncbi.nlm.nih.gov/pubmed/26160843

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