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miR-200c dampens cancer cell migration via regulation of protein kinase a subunits

Expression of miR-200c is a molecular switch to determine cellular fate towards a mesenchymal or epithelial phenotype. miR-200c suppresses the early steps of tumor progression by preventing epithelial-mesenchymal transition (EMT) and intravasation of tumor cells. Unraveling the underlying molecular...

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Detalles Bibliográficos
Autores principales: Sigloch, Florian Christoph, Burk, Ulrike Christina, Biniossek, Martin Lothar, Brabletz, Thomas, Schilling, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695158/
https://www.ncbi.nlm.nih.gov/pubmed/26203557