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Humanized anti-hepatocyte growth factor (HGF) antibody suppresses innate irinotecan (CPT-11) resistance induced by fibroblast-derived HGF

The growth factors derived from the microenvironment create an environment conducive to tumor growth and survival. HGF deprivation using neutralizing antibody enhanced chemosensitivity in colorectal cancer cells (CRC). We determined secreted HGF in fibroblast conditioned medium (CM). Combination tre...

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Detalles Bibliográficos
Autores principales: Woo, Jong Kyu, Kang, Ju-Hee, Kim, BoRa, Park, Byung Hee, Shin, Kum-Joo, Song, Seong-Won, Kim, Jung Ju, Kim, Hwan-Mook, Lee, Sang-Jin, Oh, Seung Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695169/
https://www.ncbi.nlm.nih.gov/pubmed/26090722