The downregulation of ΔNp63 in p53-deficient mouse epidermal tumors favors metastatic behavior

The TP63 gene codes for two major isoform types, TAp63 and ΔNp63, with probable opposite roles in tumorigenesis. The ΔNp63α protein is frequently amplified and overexpressed in different epithelial tumors. Accordingly, it has been considered a potential oncogene. Nonetheless, a possible metastatic s...

Descripción completa

Detalles Bibliográficos
Autores principales: Bornachea, Olga, López-Calderón, Fernando F., Dueñas, Marta, Segrelles, Carmen, Lorz, Corina, Suárez-Cabrera, Cristian, Marañón, María, Paradela-Dobarro, Beatriz, Santos, Mirentxu, Paramio, Jesús M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695182/
https://www.ncbi.nlm.nih.gov/pubmed/26203771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695182/
https://www.ncbi.nlm.nih.gov/pubmed/26203771

Ejemplares similares