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Ceramides promote apoptosis for virus-infected lymphoma cells through induction of ceramide synthases and viral lytic gene expression

Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent for several human cancers including primary effusion lymphoma (PEL), a rapidly progressive malignancy arising preferentially in immunocompromised patients. With conventional chemotherapy, PEL continues to portend high mortali...

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Detalles Bibliográficos
Autores principales: Dai, Lu, Trillo-Tinoco, Jimena, Bai, Aiping, Chen, Yihan, Bielawski, Jacek, Del Valle, Luis, Smith, Charles D., Ochoa, Augusto C., Qin, Zhiqiang, Parsons, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695183/
https://www.ncbi.nlm.nih.gov/pubmed/26327294