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Ceramides promote apoptosis for virus-infected lymphoma cells through induction of ceramide synthases and viral lytic gene expression
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent for several human cancers including primary effusion lymphoma (PEL), a rapidly progressive malignancy arising preferentially in immunocompromised patients. With conventional chemotherapy, PEL continues to portend high mortali...
Autores principales: | Dai, Lu, Trillo-Tinoco, Jimena, Bai, Aiping, Chen, Yihan, Bielawski, Jacek, Del Valle, Luis, Smith, Charles D., Ochoa, Augusto C., Qin, Zhiqiang, Parsons, Chris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695183/ https://www.ncbi.nlm.nih.gov/pubmed/26327294 |
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