5mC-hydroxylase activity is influenced by the PARylation of TET1 enzyme

5-hydroxymethylcytosine is a new epigenetic modification deriving from the oxidation of 5-methylcytosine by the TET hydroxylase enzymes. DNA hydroxymethylation drives DNA demethylation events and is involved in the control of gene expression. Deregulation of TET enzymes causes developmental defects...

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Detalles Bibliográficos
Autores principales: Ciccarone, Fabio, Valentini, Elisabetta, Zampieri, Michele, Caiafa, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695189/
https://www.ncbi.nlm.nih.gov/pubmed/26136340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695189/
https://www.ncbi.nlm.nih.gov/pubmed/26136340

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