Endothelial Jagged1 promotes solid tumor growth through both pro-angiogenic and angiocrine functions

Angiogenesis is an essential process required for tumor growth and progression. The Notch signaling pathway has been identified as a key regulator of the neo-angiogenic process. Jagged-1 (Jag1) is a Notch ligand required for embryonic and retinal vascular development, which direct contribution to th...

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Detalles Bibliográficos
Autores principales: Pedrosa, Ana-Rita, Trindade, Alexandre, Carvalho, Catarina, Graça, José, Carvalho, Sandra, Peleteiro, Maria C., Adams, Ralf H., Duarte, António
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695194/
https://www.ncbi.nlm.nih.gov/pubmed/26213336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695194/
https://www.ncbi.nlm.nih.gov/pubmed/26213336

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