RNAi therapy targeting KRAS in combination with chemotherapy for locally advanced pancreatic cancer patients

PURPOSE: The miniature biodegradable implant siG12D-LODER™ was inserted into a tumor and released a siRNA drug against KRAS(G12D) along four months. This novel siRNA based drug was studied, in combination with chemotherapy, as targeted therapy for Locally Advanced Pancreatic Cancer (LAPC). METHODS:...

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Detalles Bibliográficos
Autores principales: Golan, Talia, Khvalevsky, Elina Zorde, Hubert, Ayala, Gabai, Rachel Malka, Hen, Naama, Segal, Amiel, Domb, Abraham, Harari, Gil, David, Eliel Ben, Raskin, Stephen, Goldes, Yuri, Goldin, Eran, Eliakim, Rami, Lahav, Maor, Kopleman, Yael, Dancour, Alain, Shemi, Amotz, Galun, Eithan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Clinical Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695206/
https://www.ncbi.nlm.nih.gov/pubmed/26009994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695206/
https://www.ncbi.nlm.nih.gov/pubmed/26009994

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