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Intra-tumor Genetic Heterogeneity in Rectal Cancer

Colorectal cancer arises in part from the cumulative effects of multiple gene lesions. Recent studies in selected cancer types have revealed significant intra-tumor genetic heterogeneity and highlighted its potential role in disease progression and resistance to therapy. We hypothesized the existenc...

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Detalles Bibliográficos
Autores principales: Hardiman, Karin M., Ulintz, Peter J., Kuick, Rork, Hovelson, Daniel H., Gates, Christopher M., Bhasi, Ashwini, Grant, Ana Rodrigues, Liu, Jianhua, Cani, Andi K., Greenson, Joel, Tomlins, Scott, Fearon, Eric R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695247/
https://www.ncbi.nlm.nih.gov/pubmed/26568296
http://dx.doi.org/10.1038/labinvest.2015.131