Cargando…
Intra-tumor Genetic Heterogeneity in Rectal Cancer
Colorectal cancer arises in part from the cumulative effects of multiple gene lesions. Recent studies in selected cancer types have revealed significant intra-tumor genetic heterogeneity and highlighted its potential role in disease progression and resistance to therapy. We hypothesized the existenc...
Autores principales: | Hardiman, Karin M., Ulintz, Peter J., Kuick, Rork, Hovelson, Daniel H., Gates, Christopher M., Bhasi, Ashwini, Grant, Ana Rodrigues, Liu, Jianhua, Cani, Andi K., Greenson, Joel, Tomlins, Scott, Fearon, Eric R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695247/ https://www.ncbi.nlm.nih.gov/pubmed/26568296 http://dx.doi.org/10.1038/labinvest.2015.131 |
Ejemplares similares
-
Rectal cancer sub-clones respond differentially to neoadjuvant therapy()
por: Frydrych, Lynn M, et al.
Publicado: (2019) -
Rapamycin Inhibition of Polyposis and Progression to Dysplasia in a Mouse Model
por: Hardiman, Karin M., et al.
Publicado: (2014) -
BRAF(V600E) cooperates with CDX2 inactivation to promote serrated colorectal tumorigenesis
por: Sakamoto, Naoya, et al.
Publicado: (2017) -
Next generation sequencing of vitreoretinal lymphomas from small-volume intraocular liquid biopsies: new routes to targeted therapies
por: Cani, Andi K., et al.
Publicado: (2016) -
Comprehensive serial molecular profiling of an “N of 1” exceptional non-responder with metastatic prostate cancer progressing to small cell carcinoma on treatment
por: Kadakia, Kunal C., et al.
Publicado: (2015)