Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA

We present the crystal structure of the junction-resolving enzyme GEN1 bound to DNA at 2.5 Å resolution. The structure of the GEN1 protein reveals it to have an elaborated FEN-XPG family fold that is modified for its role in four-way junction resolution. The functional unit in the crystal is a monom...

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Detalles Bibliográficos
Autores principales: Liu, Yijin, Freeman, Alasdair D.J., Déclais, Anne-Cécile, Wilson, Timothy J., Gartner, Anton, Lilley, David M.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695337/
https://www.ncbi.nlm.nih.gov/pubmed/26686639
http://dx.doi.org/10.1016/j.celrep.2015.11.042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695337/
https://www.ncbi.nlm.nih.gov/pubmed/26686639
http://dx.doi.org/10.1016/j.celrep.2015.11.042

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