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Mesenchymal Cancer Cell-Stroma Crosstalk Promotes Niche Activation, Epithelial Reversion, and Metastatic Colonization

During metastatic colonization, tumor cells must establish a favorable microenvironment or niche that will sustain their growth. However, both the temporal and molecular details of this process remain poorly understood. Here, we found that metastatic initiating cells (MICs) exhibit a high capacity f...

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Detalles Bibliográficos
Autores principales: del Pozo Martin, Yaiza, Park, Danielle, Ramachandran, Anassuya, Ombrato, Luigi, Calvo, Fernando, Chakravarty, Probir, Spencer-Dene, Bradley, Derzsi, Stefanie, Hill, Caroline S., Sahai, Erik, Malanchi, Ilaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695340/
https://www.ncbi.nlm.nih.gov/pubmed/26670048
http://dx.doi.org/10.1016/j.celrep.2015.11.025