Heparins attenuated histone-mediated cytotoxicity in vitro and improved the survival in a rat model of histone-induced organ dysfunction

BACKGROUND: The beneficial effects of heparin in the treatment of severe sepsis, septic shock, and sepsis-associated disseminated intravascular coagulation (DIC) have recently been reported. However, the mechanisms underlying the therapeutic benefits of heparin in these conditions have not yet been...

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Detalles Bibliográficos
Autores principales: Iba, Toshiaki, Hashiguchi, Naoyuki, Nagaoka, Isao, Tabe, Yoko, Kadota, Katsuhiko, Sato, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695463/
https://www.ncbi.nlm.nih.gov/pubmed/26715580
http://dx.doi.org/10.1186/s40635-015-0072-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695463/
https://www.ncbi.nlm.nih.gov/pubmed/26715580
http://dx.doi.org/10.1186/s40635-015-0072-z

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