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TERT promoter mutations are a rare event in gastrointestinal stromal tumors

Recently, the impact of telomere dysregulation on malignant progression has been reported in many cancers. A few studies have examined TERT promoter mutations in gastrointestinal stromal tumors (GISTs). Irregular telomerase activation can be maintained by TERT hot spot alterations and alternative le...

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Detalles Bibliográficos
Autores principales: Akaike, Keisuke, Toda-Ishii, Midori, Suehara, Yoshiyuki, Mukaihara, Kenta, Kubota, Daisuke, Mitani, Keiko, Takagi, Tatsuya, Kaneko, Kazuo, Yao, Takashi, Saito, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695492/
https://www.ncbi.nlm.nih.gov/pubmed/26753123
http://dx.doi.org/10.1186/s40064-015-1606-2