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Tumour exosomes display differential mechanical and complement activation properties dependent on malignant state: implications in endothelial leakiness
BACKGROUND: Exosomes have been implicated in tumour progression and metastatic spread. Little is known of the effect of mechanical and innate immune interactions of malignant cell-derived exosomes on endothelial integrity, which may relate to increased extravasation of circulating tumour cells and,...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Co-Action Publishing
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695623/ https://www.ncbi.nlm.nih.gov/pubmed/26714455 http://dx.doi.org/10.3402/jev.v4.29685 |