Tumour exosomes display differential mechanical and complement activation properties dependent on malignant state: implications in endothelial leakiness

BACKGROUND: Exosomes have been implicated in tumour progression and metastatic spread. Little is known of the effect of mechanical and innate immune interactions of malignant cell-derived exosomes on endothelial integrity, which may relate to increased extravasation of circulating tumour cells and,...

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Detalles Bibliográficos
Autores principales: Whitehead, Bradley, Wu, LinPing, Hvam, Michael Lykke, Aslan, Husnu, Dong, Mingdong, Dyrskjøt, Lars, Ostenfeld, Marie Stampe, Moghimi, Seyed Moein, Howard, Kenneth Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2015
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695623/
https://www.ncbi.nlm.nih.gov/pubmed/26714455
http://dx.doi.org/10.3402/jev.v4.29685

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