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Arsenic and Mercury Containing Traditional Chinese Medicine (Realgar and Cinnabar) Strongly Inhibit Organic Anion Transporters, Oat1 and Oat3, In Vivo in Mice

Toxic heavy metals, including mercury (Hg) and arsenic (As), accumulate preferentially in kidneys and always cause acute renal failure. The aim of this study was to investigate whether these samples affect organic anion transporters, Oat1 and Oat3, in vivo in mice kidney. Mice (n = 10) were orally t...

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Detalles Bibliográficos
Autores principales: Yu, Wen-Hao, Zhang, Na, Qi, Jin-Feng, Sun, Chen, Wang, Yong-Hui, Lin, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695662/
https://www.ncbi.nlm.nih.gov/pubmed/26788513
http://dx.doi.org/10.1155/2015/863971