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Non-Monotonic Survival of Staphylococcus aureus with Respect to Ciprofloxacin Concentration Arises from Prophage-Dependent Killing of Persisters

Staphylococcus aureus is a notorious pathogen with a propensity to cause chronic, non-healing wounds. Bacterial persisters have been implicated in the recalcitrance of S. aureus infections, and this motivated us to examine the persistence of S. aureus to ciprofloxacin, a quinolone antibiotic. Upon t...

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Detalles Bibliográficos
Autores principales: Sandvik, Elizabeth L., Fazen, Christopher H., Henry, Theresa C., Mok, Wendy W.K., Brynildsen, Mark P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695809/
https://www.ncbi.nlm.nih.gov/pubmed/26593926
http://dx.doi.org/10.3390/ph8040778