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Active Nuclear Import of Membrane Proteins Revisited

It is poorly understood how membrane proteins destined for the inner nuclear membrane pass the crowded environment of the Nuclear Pore Complex (NPC). For the Saccharomyces cerevisiae proteins Src1/Heh1 and Heh2, a transport mechanism was proposed where the transmembrane domains diffuse through the m...

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Detalles Bibliográficos
Autores principales: Laba, Justyna K., Steen, Anton, Popken, Petra, Chernova, Alina, Poolman, Bert, Veenhoff, Liesbeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695851/
https://www.ncbi.nlm.nih.gov/pubmed/26473931
http://dx.doi.org/10.3390/cells4040653