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Role of the Polycystins in Cell Migration, Polarity, and Tissue Morphogenesis

Cystic kidney diseases (CKD) is a class of disorders characterized by ciliary dysfunction and, therefore, belonging to the ciliopathies. The prototype CKD is autosomal dominant polycystic kidney disease (ADPKD), whose mutated genes encode for two membrane-bound proteins, polycystin-1 (PC-1) and poly...

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Detalles Bibliográficos
Autores principales: Nigro, Elisa Agnese, Castelli, Maddalena, Boletta, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695853/
https://www.ncbi.nlm.nih.gov/pubmed/26529018
http://dx.doi.org/10.3390/cells4040687