Cargando…
Role of the Polycystins in Cell Migration, Polarity, and Tissue Morphogenesis
Cystic kidney diseases (CKD) is a class of disorders characterized by ciliary dysfunction and, therefore, belonging to the ciliopathies. The prototype CKD is autosomal dominant polycystic kidney disease (ADPKD), whose mutated genes encode for two membrane-bound proteins, polycystin-1 (PC-1) and poly...
Autores principales: | Nigro, Elisa Agnese, Castelli, Maddalena, Boletta, Alessandra |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695853/ https://www.ncbi.nlm.nih.gov/pubmed/26529018 http://dx.doi.org/10.3390/cells4040687 |
Ejemplares similares
-
Polycystin-1 Regulates Actomyosin Contraction and the Cellular Response to Extracellular Stiffness
por: Nigro, Elisa Agnese, et al.
Publicado: (2019) -
Polycystin-1 Binds Par3/aPKC and Controls Convergent Extension During Renal Tubular Morphogenesis
por: Castelli, Maddalena, et al.
Publicado: (2013) -
Regulation of the microtubular cytoskeleton by Polycystin-1 favors focal adhesions turnover to modulate cell adhesion and migration
por: Castelli, Maddalena, et al.
Publicado: (2015) -
Emerging evidence of a link between the polycystins and the mTOR pathways
por: Boletta, Alessandra
Publicado: (2009) -
mTORC1-mediated inhibition of polycystin-1 expression drives renal cyst formation in tuberous sclerosis complex
por: Pema, Monika, et al.
Publicado: (2016)