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Histone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune Therapy

The treatment of melanoma has been revolutionized by new therapies targeting MAPK signaling or the immune system. Unfortunately these therapies are hindered by either primary resistance or the development of acquired resistance. Resistance mechanisms involving somatic mutations in genes associated w...

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Detalles Bibliográficos
Autores principales: Gallagher, Stuart J, Tiffen, Jessamy C, Hersey, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695870/
https://www.ncbi.nlm.nih.gov/pubmed/26426052
http://dx.doi.org/10.3390/cancers7040870