Clinical Implications of Hedgehog Pathway Signaling in Prostate Cancer

Activity in the Hedgehog pathway, which regulates GLI-mediated transcription, is important in organogenesis and stem cell regulation in self-renewing organs, but is pathologically elevated in many human malignancies. Mutations leading to constitutive activation of the pathway have been implicated in...

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Detalles Bibliográficos
Autores principales: Suzman, Daniel L., Antonarakis, Emmanuel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695871/
https://www.ncbi.nlm.nih.gov/pubmed/26426053
http://dx.doi.org/10.3390/cancers7040871