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Clinical Implications of Hedgehog Pathway Signaling in Prostate Cancer
Activity in the Hedgehog pathway, which regulates GLI-mediated transcription, is important in organogenesis and stem cell regulation in self-renewing organs, but is pathologically elevated in many human malignancies. Mutations leading to constitutive activation of the pathway have been implicated in...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695871/ https://www.ncbi.nlm.nih.gov/pubmed/26426053 http://dx.doi.org/10.3390/cancers7040871 |