Targeting the Hedgehog Pathway in Pediatric Medulloblastoma

Medulloblastoma (MB), a primitive neuroectomal tumor of the cerebellum, is the most common malignant pediatric brain tumor. The cause of MB is largely unknown, but aberrant activation of Hedgehog (Hh) pathway is responsible for ~30% of MB. Despite aggressive treatment with surgical resection, radiat...

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Detalles Bibliográficos
Autores principales: Huang, Sherri Y., Yang, Jer-Yen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695880/
https://www.ncbi.nlm.nih.gov/pubmed/26512695
http://dx.doi.org/10.3390/cancers7040880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695880/
https://www.ncbi.nlm.nih.gov/pubmed/26512695
http://dx.doi.org/10.3390/cancers7040880

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