Cargando…

Hypermethylation of MAPK13 Promoter in Oesophageal Squamous Cell Carcinoma Is Associated with Loss of p38δ MAPK Expression

The loss of tumour suppressor gene function is a hallmark of malignant transformation and can occur by a variety of genetic and/or epigenetic alterations. We have previously characterised p38δ mitogen-activated protein kinase (MAPK) as a tumour suppressor in oesophageal squamous cell carcinoma (OESC...

Descripción completa

Detalles Bibliográficos
Autores principales: O′Callaghan, Carol, Fanning, Liam J., Barry, Orla P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695881/
https://www.ncbi.nlm.nih.gov/pubmed/26512696
http://dx.doi.org/10.3390/cancers7040881