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Meta-Analysis of DNA Tumor-Viral Integration Site Selection Indicates a Role for Repeats, Gene Expression and Epigenetics

Oncoviruses cause tremendous global cancer burden. For several DNA tumor viruses, human genome integration is consistently associated with cancer development. However, genomic features associated with tumor viral integration are poorly understood. We sought to define genomic determinants for 1897 lo...

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Detalles Bibliográficos
Autores principales: Doolittle-Hall, Janet M., Cunningham Glasspoole, Danielle L., Seaman, William T., Webster-Cyriaque, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695887/
https://www.ncbi.nlm.nih.gov/pubmed/26569308
http://dx.doi.org/10.3390/cancers7040887