Aberrant GLI1 Activation in DNA Damage Response, Carcinogenesis and Chemoresistance

The canonical hedgehog (HH) pathway is a multicomponent signaling cascade (HH, protein patched homolog 1 (PTCH1), smoothened (SMO)) that plays a pivotal role during embryonic development through activation of downstream effector molecules, namely glioma-associated oncogene homolog 1 (GLI1), GLI2 and...

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Detalles Bibliográficos
Autores principales: Palle, Komaraiah, Mani, Chinnadurai, Tripathi, Kaushlendra, Athar, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695894/
https://www.ncbi.nlm.nih.gov/pubmed/26633513
http://dx.doi.org/10.3390/cancers7040894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695894/
https://www.ncbi.nlm.nih.gov/pubmed/26633513
http://dx.doi.org/10.3390/cancers7040894

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