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Association Studies of HFE C282Y and H63D Variants with Oral Cancer Risk and Iron Homeostasis Among Whites and Blacks

Background: Polymorphisms in the hemochromatosis (HFE) gene are associated with excessive iron absorption from the diet, and pro-oxidant effects of iron accumulation are thought to be a risk factor for several types of cancer. Methods: The C282Y (rs1800562) and H63D (rs1799945) polymorphisms were ge...

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Detalles Bibliográficos
Autores principales: Jones, Nathan R., Ashmore, Joseph H., Lee, Sang Y., Richie, John P., Lazarus, Philip, Muscat, Joshua E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695898/
https://www.ncbi.nlm.nih.gov/pubmed/26690219
http://dx.doi.org/10.3390/cancers7040898