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Deficiency of iPLA(2)β Primes Immune Cells for Proinflammation: Potential Involvement in Age-Related Mesenteric Lymph Node Lymphoma

Proinflammation can predispose the body to autoimmunity and cancer. We have reported that iPLA(2)β(−/−) mice are susceptible to autoimmune hepatitis and colitis. Here we determined whether cytokine release by immune cells could be affected by iPLA(2)β deficiency alone or combined with CD95/FasL-anti...

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Detalles Bibliográficos
Autores principales: Inhoffen, Johannes, Tuma-Kellner, Sabine, Straub, Beate, Stremmel, Wolfgang, Chamulitrat, Walee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695901/
https://www.ncbi.nlm.nih.gov/pubmed/26690222
http://dx.doi.org/10.3390/cancers7040901