A new strategy for enhancing imputation quality of rare variants from next-generation sequencing data via combining SNP and exome chip data

BACKGROUND: Rare variants have gathered increasing attention as a possible alternative source of missing heritability. Since next generation sequencing technology is not yet cost-effective for large-scale genomic studies, a widely used alternative approach is imputation. However, the imputation appr...

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Detalles Bibliográficos
Autores principales: Kim, Young Jin, Lee, Juyoung, Kim, Bong-Jo, Park, Taesung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696174/
https://www.ncbi.nlm.nih.gov/pubmed/26715385
http://dx.doi.org/10.1186/s12864-015-2192-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696174/
https://www.ncbi.nlm.nih.gov/pubmed/26715385
http://dx.doi.org/10.1186/s12864-015-2192-y

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