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Ligand engagement of Toll-like receptors regulates their expression in cortical microglia and astrocytes

BACKGROUND: Toll-like receptor (TLR) activation on microglia and astrocytes are key elements in neuroinflammation which accompanies a number of neurological disorders. While TLR activation on glia is well-established to up-regulate pro-inflammatory mediator expression, much less is known about how l...

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Detalles Bibliográficos
Autores principales: Marinelli, Carla, Di Liddo, Rosa, Facci, Laura, Bertalot, Thomas, Conconi, Maria Teresa, Zusso, Morena, Skaper, Stephen D., Giusti, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696218/
https://www.ncbi.nlm.nih.gov/pubmed/26714634
http://dx.doi.org/10.1186/s12974-015-0458-6