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Adopting the rapamycin trapping assay to track the trafficking of murine MHC class I alleles, H-2K(b)

BACKGROUND: In mammalian cells, the quality control (QC) of properly folded proteins is monitored in the early secretory pathway, particularly in the endoplasmic reticulum (ER). Several proteins, including our protein of interest, major histocompatibility complex class I (MHC class I), can bypass th...

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Detalles Bibliográficos
Autores principales: Ghanem, Esther, Al-Balushi, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696223/
https://www.ncbi.nlm.nih.gov/pubmed/26714929
http://dx.doi.org/10.1186/s12860-015-0077-1