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Polymorphisms in the IL-6 and IL-6R receptor genes as new diagnostic biomarkers of acute appendicitis: a study on two candidate genes in pediatric patients with acute appendicitis

BACKGROUND: Acute appendicitis (AA) (OMIM: 107700) is an inflammatory disease which is characterized by appendiceal inflammation. Genetic and environmental factors contribute to the development of AA. Especially, multiple genetic factors appear to be promising in the explanation of etiopathogenesis...

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Detalles Bibliográficos
Autores principales: Sarsu, Sevgi Büyükbeşe, Yılmaz, Şenay Görücü, Bayram, Ali, Denk, Affan, Kargun, Kürşat, Sungur, Mehmet Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696224/
https://www.ncbi.nlm.nih.gov/pubmed/26714766
http://dx.doi.org/10.1186/s13052-015-0206-7