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What’s in your next-generation sequence data? An exploration of unmapped DNA and RNA sequence reads from the bovine reference individual

BACKGROUND: Next-generation sequencing projects commonly commence by aligning reads to a reference genome assembly. While improvements in alignment algorithms and computational hardware have greatly enhanced the efficiency and accuracy of alignments, a significant percentage of reads often remain un...

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Detalles Bibliográficos
Autores principales: Whitacre, Lynsey K., Tizioto, Polyana C., Kim, JaeWoo, Sonstegard, Tad S., Schroeder, Steven G., Alexander, Leeson J., Medrano, Juan F., Schnabel, Robert D., Taylor, Jeremy F., Decker, Jared E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696311/
https://www.ncbi.nlm.nih.gov/pubmed/26714747
http://dx.doi.org/10.1186/s12864-015-2313-7