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Enhanced production of recombinant proteins with Corynebacterium glutamicum by deletion of insertion sequences (IS elements)
BACKGROUND: In most bacteria, various jumping genetic elements including insertion sequences elements (IS elements) cause a variety of genetic rearrangements resulting in harmful effects such as genome and recombinant plasmid instability. The genetic stability of a plasmid in a host is critical for...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696348/ https://www.ncbi.nlm.nih.gov/pubmed/26715464 http://dx.doi.org/10.1186/s12934-015-0401-7 |