Making sense of GWAS: using epigenomics and genome engineering to understand the functional relevance of SNPs in non-coding regions of the human genome

Considerable progress towards an understanding of complex diseases has been made in recent years due to the development of high-throughput genotyping technologies. Using microarrays that contain millions of single-nucleotide polymorphisms (SNPs), Genome Wide Association Studies (GWASs) have identifi...

Descripción completa

Detalles Bibliográficos
Autores principales: Tak, Yu Gyoung, Farnham, Peggy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696349/
https://www.ncbi.nlm.nih.gov/pubmed/26719772
http://dx.doi.org/10.1186/s13072-015-0050-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696349/
https://www.ncbi.nlm.nih.gov/pubmed/26719772
http://dx.doi.org/10.1186/s13072-015-0050-4

Ejemplares similares