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Parsing interindividual drug variability: an emerging role for systems pharmacology

There is notable interindividual heterogeneity in drug response, affecting both drug efficacy and toxicity, resulting in patient harm and the inefficient utilization of limited healthcare resources. Pharmacogenomics is at the forefront of research to understand interindividual drug response variabil...

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Detalles Bibliográficos
Autores principales: Turner, Richard M, Park, B Kevin, Pirmohamed, Munir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696409/
https://www.ncbi.nlm.nih.gov/pubmed/25950758
http://dx.doi.org/10.1002/wsbm.1302