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Comparative Molecular Dynamics Studies of Human DNA Polymerase η

[Image: see text] High-energy ultraviolet radiation damages DNA through the formation of cyclobutane pyrimidine dimers, which stall replication. When the lesion is a thymine–thymine dimer (TTD), human DNA polymerase η (Pol η) assists in resuming the replication process by inserting nucleotides oppos...

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Detalles Bibliográficos
Autores principales: Ucisik, Melek N., Hammes-Schiffer, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696480/
https://www.ncbi.nlm.nih.gov/pubmed/26562587
http://dx.doi.org/10.1021/acs.jcim.5b00606