P2X7 receptor activation regulates rapid unconventional export of transglutaminase-2

Transglutaminases (denoted TG or TGM) are externalized from cells via an unknown unconventional secretory pathway. Here, we show for the first time that purinergic signaling regulates active secretion of TG2 (also known as TGM2), an enzyme with a pivotal role in stabilizing extracellular matrices an...

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Detalles Bibliográficos
Autores principales: Adamczyk, Magdalena, Griffiths, Rhiannon, Dewitt, Sharon, Knäuper, Vera, Aeschlimann, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696497/
https://www.ncbi.nlm.nih.gov/pubmed/26542019
http://dx.doi.org/10.1242/jcs.175968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696497/
https://www.ncbi.nlm.nih.gov/pubmed/26542019
http://dx.doi.org/10.1242/jcs.175968

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