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Cooperativity in Binding Processes: New Insights from Phenomenological Modeling

Cooperative binding is one of the most interesting and not fully understood phenomena involved in control and regulation of biological processes. Here we analyze the simplest phenomenological model that can account for cooperativity (i.e. ligand binding to a macromolecule with two binding sites) by...

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Detalles Bibliográficos
Autores principales: Cattoni, Diego I., Chara, Osvaldo, Kaufman, Sergio B., González Flecha, F. Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696654/
https://www.ncbi.nlm.nih.gov/pubmed/26717487
http://dx.doi.org/10.1371/journal.pone.0146043