Identification of Novel Small Organic Compounds with Diverse Structures for the Induction of Epstein-Barr Virus (EBV) Lytic Cycle in EBV-Positive Epithelial Malignancies

Phorbol esters, which are protein kinase C (PKC) activators, and histone deacetylase (HDAC) inhibitors, which cause enhanced acetylation of cellular proteins, are the main classes of chemical inducers of Epstein-Barr virus (EBV) lytic cycle in latently EBV-infected cells acting through the PKC pathw...

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Detalles Bibliográficos
Autores principales: Choi, Chung King, Ho, Dona N., Hui, Kwai Fung, Kao, Richard Y., Chiang, Alan K. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696655/
https://www.ncbi.nlm.nih.gov/pubmed/26717578
http://dx.doi.org/10.1371/journal.pone.0145994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696655/
https://www.ncbi.nlm.nih.gov/pubmed/26717578
http://dx.doi.org/10.1371/journal.pone.0145994

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