Cargando…

Identification of Novel Small Organic Compounds with Diverse Structures for the Induction of Epstein-Barr Virus (EBV) Lytic Cycle in EBV-Positive Epithelial Malignancies

Phorbol esters, which are protein kinase C (PKC) activators, and histone deacetylase (HDAC) inhibitors, which cause enhanced acetylation of cellular proteins, are the main classes of chemical inducers of Epstein-Barr virus (EBV) lytic cycle in latently EBV-infected cells acting through the PKC pathw...

Descripción completa

Detalles Bibliográficos
Autores principales:	Choi, Chung King, Ho, Dona N., Hui, Kwai Fung, Kao, Richard Y., Chiang, Alan K. S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696655/ https://www.ncbi.nlm.nih.gov/pubmed/26717578 http://dx.doi.org/10.1371/journal.pone.0145994

Ejemplares similares

Intracellular Iron Chelation by a Novel Compound, C7, Reactivates Epstein–Barr Virus (EBV) Lytic Cycle via the ERK-Autophagy Axis in EBV-Positive Epithelial Cancers
por: Yiu, Stephanie Pei Tung, et al.
Publicado: (2018)

Therapies based on targeting Epstein‐Barr virus lytic replication for EBV‐associated malignancies
por: Li, Hongde, et al.
Publicado: (2018)

Lytic Induction Therapy against Epstein–Barr Virus-Associated Malignancies: Past, Present, and Future
por: Yiu, Stephanie Pei Tung, et al.
Publicado: (2020)

Epstein–Barr Virus (EBV) Rta-Mediated EBV and Kaposi's Sarcoma-Associated Herpesvirus Lytic Reactivations in 293 Cells
por: Chen, Yen-Ju, et al.
Publicado: (2011)

Burkitt's lymphoma: differential killing of Epstein-Barr virus (EBV) (+) and EBV(-) Burkitt lymphoma cells in vitro and dose-dependent lytic induction by bortezomib in vivo
por: Dufresne, AL, et al.
Publicado: (2009)

Opportunities to Target the Life Cycle of Epstein-Barr Virus (EBV) in EBV-Associated Lymphoproliferative Disorders
por: Dugan, James P., et al.
Publicado: (2019)

Complexities associated with expression of Epstein–Barr virus (EBV) lytic origins of DNA replication
por: Xue, Shao-An, et al.
Publicado: (2007)

Counteracting survival functions of EBNA3C in Epstein-Barr virus (EBV)-driven lymphoproliferative diseases by combination of SAHA and bortezomib
por: Hui, Kwai Fung, et al.
Publicado: (2018)

Epstein–Barr Virus (EBV) Epithelial Associated Malignancies: Exploring Pathologies and Current Treatments
por: Shechter, Oren, et al.
Publicado: (2022)

Molecular Epidemiology of Epstein-Barr virus (EBV) in Patients with Hematologic Malignancies
por: Tabibzadeh, Alireza, et al.
Publicado: (2020)

Epstein–Barr virus (EBV) deletions as biomarkers of response to treatment of chronic active EBV
por: Venturini, Cristina, et al.
Publicado: (2021)

Induction of epstein-barr virus (EBV) lytic cycle in vitro causes lipid peroxidation, protein oxidation and DNA damage in lymphoblastoid B cell lines
por: Gargouri, Bochra, et al.
Publicado: (2011)

Contribution of the KSHV and EBV lytic cycles to tumourigenesis
por: Manners, Oliver, et al.
Publicado: (2018)

Prognostic Epstein-Barr Virus (EBV) miRNA biomarkers for survival outcome in EBV-associated epithelial malignancies: Systematic review and meta-analysis
por: Abusalah, Mai Abdel Haleem, et al.
Publicado: (2022)

Epstein-Barr Virus (EBV)-Related Lymphoproliferative Disorders in Ataxia Telangiectasia: Does ATM Regulate EBV Life Cycle?
por: Tatfi, Moussab, et al.
Publicado: (2019)

Leflunomide/teriflunomide inhibit Epstein-Barr virus (EBV)-induced lymphoproliferative disease and lytic viral replication
por: Bilger, Andrea, et al.
Publicado: (2017)

Lytic EBV infection investigated by detection of Soluble Epstein-Barr virus ZEBRA in the serum of patients with PTLD
por: Habib, Mohammed, et al.
Publicado: (2017)

Autophagy-Dependent Reactivation of Epstein-Barr Virus Lytic Cycle and Combinatorial Effects of Autophagy-Dependent and Independent Lytic Inducers in Nasopharyngeal Carcinoma
por: Yiu, Stephanie Pei Tung, et al.
Publicado: (2019)

Hippo signaling effectors YAP and TAZ induce Epstein-Barr Virus (EBV) lytic reactivation through TEADs in epithelial cells
por: Van Sciver, Nicholas, et al.
Publicado: (2021)

Epstein-Barr Virus (EBV)-Associated Haemophagocytic Syndrome
por: Torti, Lorenza, et al.
Publicado: (2012)

Epstein-Barr Virus (EBV)-associated Gastric Carcinoma
por: Iizasa, Hisashi, et al.
Publicado: (2012)

Epstein–Barr virus (EBV)-associated epithelial and non-epithelial lesions of the oral cavity
por: Kikuchi, Kentaro, et al.
Publicado: (2017)

Epstein-Barr virus (EBV)-associated miRNAs are important for the maintenance of EBV transformed B cells
por: Linnstaedt, Sarah, et al.
Publicado: (2010)

Epstein–Barr virus (EBV) and polyomaviruses are detectable in oropharyngeal cancer and EBV may have prognostic impact
por: Carpén, Timo, et al.
Publicado: (2020)

Updates on Epstein–Barr Virus (EBV)-Associated Nasopharyngeal Carcinoma: Emphasis on the Latent Gene Products of EBV
por: Ahmed, Naveed, et al.
Publicado: (2022)

Pathogenic Role of Exosomes in Epstein-Barr Virus (EBV)-Associated Cancers
por: Teow, Sin-Yeang, et al.
Publicado: (2017)

Identification of target antigens for the human cytotoxic T cell response to Epstein-Barr virus (EBV): implications for the immune control of EBV-positive malignancies
Publicado: (1992)

The Characteristics of Epstein‐Barr Virus (EBV)‐positive Diffuse Large B‐Cell Lymphoma: Comparison between EBV(+) and EBV(‐) Cases in Japanese Population
por: Kuze, Tetuo, et al.
Publicado: (2000)

Dendrosomal nanocurcumin prevents EBV-associated cell transformation by targeting the lytic cycle genes of the Epstein-Barr virus in the generation of lymphoblastoid cell line
por: Cheragh, Mahboobeh, et al.
Publicado: (2023)

Curcuminoids as EBV Lytic Activators for Adjuvant Treatment in EBV-Positive Carcinomas
por: Ramayanti, Octavia, et al.
Publicado: (2018)

DNA Damage Signaling Is Induced in the Absence of Epstein—Barr Virus (EBV) Lytic DNA Replication and in Response to Expression of ZEBRA
por: Wang'ondu, Ruth, et al.
Publicado: (2015)

Risk factors for Hodgkin's disease by Epstein-Barr virus (EBV) status: prior infection by EBV and other agents
por: Alexander, F E, et al.
Publicado: (2000)

The roles of DNA methylation on the promotor of the Epstein–Barr virus (EBV) gene and the genome in patients with EBV-associated diseases
por: Zhang, Linlin, et al.
Publicado: (2022)

Epstein-Barr Virus (EBV) detection and typing by PCR: a contribution to diagnostic screening of EBV-positive Burkitt's lymphoma
por: Hassan, Rocío, et al.
Publicado: (2006)

Genome-wide analysis of Epstein-Barr virus (EBV) isolated from EBV-associated gastric carcinoma (EBVaGC)
por: Liu, Ying, et al.
Publicado: (2015)

Correction to: The roles of DNA methylation on the promotor of the Epstein–Barr virus (EBV) gene and the genome in patients with EBV‑associated diseases
por: Zhang, Linlin, et al.
Publicado: (2022)

Prevalence of Epstein–Barr virus (EBV) in Iranian Breast Carcinoma Patients
por: Golrokh Mofrad, Morvarid, et al.
Publicado: (2020)

An Acute Presentation of Epstein-Barr Virus (EBV) Infection in an Immunocompromised Gentleman
por: Bhattacharjee, Shaumick, et al.
Publicado: (2022)

Association of Epstein-Barr virus (EBV) with lung cancer: meta-analysis
por: Chen, Yizhuo, et al.
Publicado: (2023)

Heterogeneity of the Epstein-Barr Virus (EBV) Major Internal Repeat Reveals Evolutionary Mechanisms of EBV and a Functional Defect in the Prototype EBV Strain B95-8
por: Ba abdullah, Mohammed M., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_s9235u1qpu7u8fvobpoli96s4p