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Isoalantolactone Enhances the Radiosensitivity of UMSCC-10A Cells via Specific Inhibition of Erk1/2 Phosphorylation

BACKGROUND: Although radiotherapy is one of the mainstream approaches for the treatment of head and neck squamous cell carcinoma (HNSCC), this cancer is always associated with resistance to radiation. In this study, the mechanism of action of isoalantolactone as well as its radiosensitizing effect w...

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Detalles Bibliográficos
Autores principales: Fan, Yonggang, Weng, Zhiyong, Gao, Hongguo, Hu, Jiehua, Wang, Hongyan, Li, Lihua, Liu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696678/
https://www.ncbi.nlm.nih.gov/pubmed/26716456
http://dx.doi.org/10.1371/journal.pone.0145790