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Structural Motifs Critical for In Vivo Function and Stability of the RecQ-Mediated Genome Instability Protein Rmi1

Rmi1 is a member of the Sgs1/Top3/Rmi1 (STR) complex of Saccharomyces cerevisiae and has been implicated in binding and catalytic enhancement of Top3 in the dissolution of double Holliday junctions. Deletion of RMI1 results in a severe growth defect resembling that of top3Δ. Despite the importance o...

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Detalles Bibliográficos
Autores principales: Kennedy, Jessica A., Syed, Salahuddin, Schmidt, Kristina H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696737/
https://www.ncbi.nlm.nih.gov/pubmed/26717309
http://dx.doi.org/10.1371/journal.pone.0145466