Molecular Dynamics Simulation Reveals Correlated Inter-Lobe Motion in Protein Lysine Methyltransferase SMYD2

SMYD proteins are an exciting field of study as they are linked to many types of cancer-related pathways. Cardiac and skeletal muscle development and function also depend on SMYD proteins opening a possible avenue for cardiac-related treatment. Previous crystal structure studies have revealed that t...

Descripción completa

Detalles Bibliográficos
Autores principales: Spellmon, Nicholas, Sun, Xiaonan, Sirinupong, Nualpun, Edwards, Brian, Li, Chunying, Yang, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696779/
https://www.ncbi.nlm.nih.gov/pubmed/26717235
http://dx.doi.org/10.1371/journal.pone.0145758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696779/
https://www.ncbi.nlm.nih.gov/pubmed/26717235
http://dx.doi.org/10.1371/journal.pone.0145758

Ejemplares similares