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Molecular Dynamics Simulation Reveals Correlated Inter-Lobe Motion in Protein Lysine Methyltransferase SMYD2
SMYD proteins are an exciting field of study as they are linked to many types of cancer-related pathways. Cardiac and skeletal muscle development and function also depend on SMYD proteins opening a possible avenue for cardiac-related treatment. Previous crystal structure studies have revealed that t...
Autores principales: | Spellmon, Nicholas, Sun, Xiaonan, Sirinupong, Nualpun, Edwards, Brian, Li, Chunying, Yang, Zhe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696779/ https://www.ncbi.nlm.nih.gov/pubmed/26717235 http://dx.doi.org/10.1371/journal.pone.0145758 |
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