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Identifying and Reducing Systematic Errors in Chromosome Conformation Capture Data
Chromosome conformation capture (3C)-based techniques have recently been used to uncover the mystic genomic architecture in the nucleus. These techniques yield indirect data on the distances between genomic loci in the form of contact frequencies that must be normalized to remove various errors. Thi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696798/ https://www.ncbi.nlm.nih.gov/pubmed/26717152 http://dx.doi.org/10.1371/journal.pone.0146007 |